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Pregnancy ResearchNeilson JP Symphysis-fundal height measurement in pregnancy (Cochrane Review) Young GL, Jewell D. Interventions for leg cramps in pregnancy (Cochrane Review) The evidence that calcium reduces cramp is weak and seems to depend on placebo effect. The evidence for sodium chloride is stronger but the results of the sodium chloride trial may no longer be relevant because of dietary changes which include an increased sodium intake in the general population. It is not possible to recommend multivitamins with mineral supplementation, as it is not clear which ingredient, if any, is helping. If a woman finds cramp troublesome in pregnancy, the best evidence is for magnesium lactate or citrate taken as 5mmol in the morning and 10mmol in the evening. Mary L. Hardy. Women's Health Series: Herbs of Special Interest to Women. J Am Pharm Assoc 40(2):234-242, 2000. � 2000 American Pharmaceutical Association.
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