Cervidil

What is Cervidil?

Cervidil is the trademark name that Forest Laboratories, Inc. uses for prostaglandin E2 vaginal insert. It is a small rectangular pouch with a retrieval cord that looks similar to a tampon. It is inserted into the vagina.

Prostaglandin is one of the chemicals that play a part in ripening the cervix. A ripe cervix is soft and stretchy, ready to respond to uterine contractions. When given vaginally, cervidil may help to ripen the cervix.

Why choose Cervidil?

Cervidil is used to "ripen" the cervix when it is agreed that your baby is safer to be born than to remain in the uterus. Cervidil is the first step in a two part induction process when the cervix is not ready to respond to contractions.

Cervidil may increase the activity of non-productive contractions when no other labor stimulation agent has been used.

Cervidil allows the mother to use the medication for the prescribed amount of time an then remove it. In some cases a mother may be able to go home after administration to wait for labor to start.

How effective is Cervidil?

Because prostaglandin E2 helps to make the connective tissue of the cervix more pliable while also stimulating contractions, it is more effective than synthetic oxytocin at inducing labor. The rates were similar for women giving birth within 12 hours, but more women had given birth within 24 hours with prostaglandin and the difference is even more pronounced at 48 hours. In addition, the rate of instrumental vaginal delivery is lower with women induced with prostaglandin E2.

This data sheet on Cervidil offers information from research trials about its efficacy.

Risks of using Cervidil

Risks for Mother

  • Gastro-intestinal effects such as nausea, vomiting and diarrhea.

  • Small risk of uterine hyperstimulation.

  • Requires continuous monitoring of baby's heart rate which decreases mobility.

  • Another form of prostaglandin E2, Prepidil, cannot be removed if hyperstimulation occurs.

Risks for Baby

  • Uterine hyperstimulation can cause abnormal fetal heart rate.

References:
Goer, Henci. The Thinking Woman's Guide to a Better Birth. 1999. New York: The Berkley Publishing Group.
Enkin, Keirse, Nilson, Crowther, Duley, Hodnett and Hofmeyr. A guide to effective care in pregnancy and childbirth Third Edition. 2000. Oxford: Oxford University Press.




You May Also Be Interested In:

What changes are being assessed during a cervical exam.

The Natural Childbirth Directory can help you find more information about birth and locate childbirth professionals.

The Coach's Notebook helps you learn tools and techniques to manage labor.

Do some self exploration to discover how you will act in labor.

Find out how exercise and nutrition can help you achieve your birth plan goals.

© Copyright 2000-2008 Jennifer VanderLaan and Birthing Naturally


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